REDWOOD CITY, Calif., Aug. 05, 2019 (GLOBE NEWSWIRE) — Allakos Inc. (the “Company”) (Nasdaq: ALLK) today announced positive results from its Phase 2 randomized, double-blind, placebo-controlled trial of AK002 in patients with eosinophilic gastritis and/or eosinophilic gastroenteritis. All AK002 dose arms showed clinically meaningful and statistically significant benefits compared to placebo on all prespecified primary and secondary endpoints, including gastrointestinal tissue eosinophil counts and patient reported disease symptoms. Statistically significant differences in patient symptoms between the active and placebo groups occurred one day following AK002 administration. In addition, patients with comorbid eosinophilic esophagitis treated with AK002 experienced statistically significant decreases in esophageal eosinophil counts and substantial reductions in patient reported dysphagia symptoms.
REDWOOD CITY, Calif., Aug. 06, 2019 (GLOBE NEWSWIRE) — Allakos Inc. (the “Company”) (Nasdaq: ALLK), a biotechnology company developing AK002 for the treatment of eosinophil and mast cell related diseases, today announced the upsizing and pricing of its previously announced underwritten public offering. The size of the offering has been increased from the previously announced $200 million of shares of the Company’s common stock to $350 million of shares of its common stock. The Company is offering 4,545,454 shares at a public offering price of $77.00 per share. The offering is expected to close on August 9, 2019, subject to the satisfaction of customary closing conditions. In connection with the offering, the Company has granted the underwriters a 30-day option to purchase up to $52.5 million of additional shares of its common stock at the public offering price, less the underwriting discounts and commissions.
REDWOOD CITY, Calif., Aug. 05, 2019 (GLOBE NEWSWIRE) — Allakos Inc. (the “Company”) (Nasdaq: ALLK), a biotechnology company developing AK002 for the treatment of eosinophil and mast cell related diseases, today announced it intends to offer and sell, subject to market and other conditions, $200 million of shares of its common stock in an underwritten public offering. In addition, Allakos expects to grant the underwriters a 30-day option to purchase up to $30 million of additional shares of the Company’s common stock. All of the shares in the proposed offering will be sold by the Company. The proposed offering is subject to market and other conditions, and there can be no assurances as to whether or when the proposed offering may be completed, or as to the actual size or terms of the proposed offering.
ST. LOUIS, MO (July 23, 2019) – Life sciences venture capital firm RiverVest Venture Partners today announced the continued expansion of its team as Derek Rapp joins as managing director and Isaac Zike, Ph.D., as senior associate.
Most recently president & CEO of JDRF, a global organization funding type 1 diabetes research, Rapp also previously served as CEO for life sciences start-up Divergence, Inc., which he led to a successful exit. He also served as head of mergers and acquisitions at a global agtech company where he led transactions totaling more than $6 billion.
FOSTER CITY, Calif., July 17, 2019 /PRNewswire/ — Mirum Pharmaceuticals, Inc., a clinical-stage therapeutics company developing a novel approach for treating cholestatic liver diseases, today announced the pricing of its initial public offering of 5,000,000 shares of its common stock at a price to the public of $15.00 per share. The gross proceeds to Mirum from the offering, before deducting underwriting discounts and commissions and estimated offering expenses, are expected to be $75,000,000.
South San Francisco, CA, JUNE 25, 2019 — InterVene Inc. today announced it has raised $15 million in a Series B financing round. The company’s BlueLeaf® Endovenous Valve Formation System is the first catheter-based solution for deep vein reflux (DVR) — the failure of venous valves in the legs — that does not require an implant.
We mourn the passing of our co-founder, partner and friend, Andrew B. Craig III. He was essential to RiverVest’s founding in 2000 and inspiration to the firm’s high professional and personal standards. We will miss him as a mentor and friend, but forever be enhanced by the great example he set.
SAN DIEGO, May 20, 2019 /PRNewswire/ — Reneo Pharmaceuticals, a clinical stage pharmaceutical company, today announced that it has completed a $50 million Series A financing to develop therapies for diseases associated with deficits in cellular metabolism and energy production. The A round was led by New Enterprise Associates. Other participants in the round include Lundbeckfonden Ventures, Pappas Capital and RiverVest Venture Partners.
TOLEDO, Ohio, May 16, 2019 /PRNewswire/ — VentureMed Group, Inc., a privately-held medical device innovator in vessel preparation for interventional treatment of peripheral arterial disease (PAD) and stenoses of arteriovenous (AV) fistulas and grafts announced today that the Company will be relocating from its current facilities in the ProMedica Innovations Center in Toledo, Ohio to Minneapolis, Minnesota as the Company continues to develop and grow.
May 7, 2019 at 4:01 PM EDT
— Substantial reduction of patient reported symptoms and physician assessed signs and symptoms —
— Improvements also observed in atopic dermatitis, asthma and allergic rhinitis —
— Conference call and webcast today at 5:00 pm ET —
REDWOOD CITY, Calif., May 07, 2019 (GLOBE NEWSWIRE) — Allakos Inc. (Nasdaq: ALLK), a biotechnology company developing AK002 for the treatment of eosinophil and mast cell related diseases, today announced positive Phase 1 results in patients with severe allergic conjunctivitis. Patients administered AK002 reported a 78% median improvement in ocular symptoms by Allergic Conjunctivitis Symptom (ACS) Score and a 71% median improvement in physician assessed signs and symptoms using the Ocular Symptom Score (OSS). In addition, patients suffering from comorbid atopic dermatitis, asthma and allergic rhinitis, despite treatment with currently available therapies, reported improvements in their symptoms while receiving AK002.
April 10, 2019
The gene therapy revolution that’s been sweeping through biotech isn’t just about humans anymore. A Penn-partnered biotech called Scout Bio has just picked up a $20 million round to step up its work on once-and-done therapies for common pet ailments. Read more